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The risk groups remain consistent: people eating plant-based or low-meat diets, adults over 50, long-term users of metformin or proton pump inhibitors, anyone with GI absorption issues, people on GLP-1 protocols with significantly reduced food intake, and heavy alcohol users

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Despite these circulating changes, controlled tracer studies indicate that whole-body and myofibrillar protein synthesis rates remain largely unchanged across menstrual phases [139,140]