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๐งช Glutathione Depletion Pathways 1. Precursor Depletion - Key bottleneck: Cysteine availability. - Source: Diet or hepatic transsulfuration (methionine โ homocysteine โ cysteine). - Failure mode: Downregulation of cystathionine ฮณโlyase (CSE) during
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cerevisiae is capable of producing monoterpenes through the mevalonic acid pathway (Figure 2D)
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