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Similarly, Mrp2 mRNA and protein expressions are unaffected, in agreement with the absence of changes in the maximum secretory rate of the Mrp2 substrate, ceftriaxone;86 lack of studies of ceftriaxone excretion under non-saturating conditions, however, does not allow changes in intrinsic transport efficiency to be ruled out

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DOI Maquart FX, Pickart L, Laurent M, et al