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In the sensitivity analyses, the effectiveness against SARS-CoV-2 BA.1, BA.2, BA.4, and BA.5 subvariants aligned with the primary findings, whereas BNT162b2 effectiveness was lower against BQ.1, XBB, and subsequent subvariants of the virus

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IV doses of 25-400 mcg/kg for safety studies Important: These are experimental doses used in animal studies and cannot be extrapolated to other species due to significant differences in metabolism, pharmacokinetics, receptor expression, peptide degradation rates, and tissue distribution patterns