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Single blinding is particularly useful in non-medical studies where you cannot use a placebo in the control group

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(2019) found that inhibiting canonical Wnt signal transduction in bone marrow stromal cells prevented the development of MDS and proposed that activation of β-catenin signalling in the bone marrow of MDS patients may be a new treatment strategy that reduces β-catenin levels or inhibits Wnt/β-catenin signalling