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Model of the regulation of antioxidant redox mechanisms. The Trx and... | Download Scientific Diagram

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The primary way SF protects BBB integrity appears to be through its activation of the Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor erythroid 2-related factor 2 (NRF2) pathway, since BBB integrity is rapidly compromised in the absence of Nrf2 transcriptional activity [32]