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Accordingly, intervention concepts are gradually shifting from broadly restorative approaches toward more mechanism-based, phenotype-matched, and time-sensitive strategies
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Like most neurons, the main metabolic pathways used by retinal ganglion cells to produce adenosine triphosphate (ATP) are glycolysis and oxidative phosphorylation ( Retinal ganglion cell metabolism is dependent on the external availability of nicotinamide adenine dinucleotide (NAD), ATP, and other metabolites
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