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Heme Oxgenase-1 in cytoprotection | Encyclopedia MDPI

[DOI] [PubMed] [Google Scholar] Morgan M

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For example, dichloroacetate (DCA), which functionally counteracts Warburg metabolism by promoting mitochondrial pyruvate oxidation, has completed a phase I study in recurrent malignant gliomas showing chronic oral dosing to be feasible and generally well tolerated [39]

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