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Food Funct 2020;11:7925–34 [DOI] [PubMed] [Google Scholar] 53.Imaeda AB, Watanabe A, Sohail MA, Mahmood S, Mohamadnejad M, Sutterwala FS, Flavell RA, Mehal WZ.Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome

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Overall, in the context of the mechanical analogy downregulation and desensitization can be metaphorically understood as phenomena that increase the "static stability" of receptor systems