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9,10 Therefore, antagonism of GLU is considered neuroprotective and can be therapeutically beneficial in managing neurodegenerative brain disorders.

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Furthermore, iE-DAP was found to elevate the expression of inflammatory markers, including NOD1, inhibitor of nuclear factor-κB (NFKBIA, IκB), nuclear factor-κB subunit p65 (RELA, NF-κB p65), IL-6, and interleukin-8 (IL-8) in cell culture (231)