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This narrative review examines current evidence surrounding platelet-rich plasma, mesenchymal stem cell therapies, peptide analogs, and evolving pharmacologic agents in the management of lumbar disc degeneration, with particular emphasis on mobility restoration and rehabilitation integration

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The functioning of the pituitary gland and the hormones it secretes decreases with aging, however, IGF-1 is capable of bypassing the pituitary gland and is able to elicit the same response as GH does