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The German BfArM and equivalent agencies (ANSM in France, AEMPS in Spain, AIFA in Italy, URPL in Poland) treat unauthorized human use of these compounds as outside the scope of the marketing authorization regime entirely
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In vitro experiments have also confirmed that XYS can reverse corticosterone-induced neurotoxicity and may have a neuroprotective effect by promoting Akt phosphorylation, which further validates the antidepressant components and pharmacological mechanism of XYS [37]
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