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Since dehalogenation of DCM leads to formaldehyde, one explanation might be that transcription of methanol dehydrogenase MxaFI, which also converts formaldehyde (Nunn and Lidstrom, cmu pathway (Vannelli et al., 6) and chemical equilibrium between free formaldehyde and methylene-tetrahydrofolate (CH 2 = H 4 F) does not favor free formaldehyde (Kallen and Jencks, 1 compounds or formate, or that mxaFI expression is not switched off in strain CM4
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Nakamura S, Shibuya M, Nakashima H, Hisamura R, Masuda N, Imagawa T, et al
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