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Moreover, Plasmodium -derived RH5 antigen binds to basigin on RBCs, causing β 2 -AR and G αs protein activation, followed by cAMP and Ca 2+ level increase, thus enabling the parasite entrance (189)

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Three different stress sensors, protein kinase RNA-like endoplasmic reticulum kinase (PERK), activating transcription factor 6 (ATF6) and inositol requiring enzyme-1 (IRE1), are activated by unfolded or misfolded proteins