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Cagrilintide's phase 2 dose-finding trial randomised 706 adults over 26 weeks, and its phase 3 monotherapy data came from the REDEFINE 1 trial, which enrolled 3,417 adults over 68 weeks across all arms

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The peptide works by increasing blood vessel formation (angiogenesis) by 129-152%, enhancing fibroblast migration to damaged tissue, and upregulating growth hormone receptors that promote cellular repair