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Pigment granuloma quantification – The detection 52,53 for pigment granuloma (“foamy pigment laden cells”) on the H&E images was developed using Random Forest classifier within HALO software (Indica Lab), finetuned to detect pigment granuloma from the liver WSIs

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Evidence supporting a role for TRPM2 in mediating afferent innocuous warmth signaling comes from a study that identified neurons expressing this channel within the dorsal root ganglion (and superior cervical and pterygopalatine ganglia) of mice that are activated within the range of 34 to 42°C (124)

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