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doi: 10.3389/fimmu.2025.1640748 147 PayneBAWilsonIJHateleyCAHorvathRSantibanez-KorefMSamuelsDCet al

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Such conjugation includes either chemical conjugation by derivitizing active chemical functional groups to both the polypeptide of the present invention and the immunogenic protein such that a covalent bond is formed, or through fusion-protein based methodology, or other methods known to the skilled artisan