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Keywords: Duchenne muscular dystrophy, protandim ® , mdx mice, dystrophin, dystrophic muscle, paraoxonase, osteopontin, oxidative stress INTRODUCTION Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder that occurs in 1 in 3,500 live male births and is the most common fatal genetic disorder in children (Emery, 1991)
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For example, functionalizing Lactobacillus rhamnosus GG with ROS-responsive nanomicelles enables targeted delivery of 18β-glycyrrhetinic acid at inflamed sites, thereby scavenging excess ROS and repairing the epithelial barrier (Zhang X
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