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Some of those are: The area around the joint section getting swollen up, tender, red, or even warm to touch Pain persisting for 3 days and more Having fever but without any other flu signs Experienced any serious injury The joints seem to be deformed The joint becomes completely immobile Suffering from major joint pain ‍ Causes There are various joint pain causes that you need to be aware of, and one of the major ones is arthritis

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Pharmacodynamics (PD) characterises what the drug does to the body — receptor engagement, downstream signalling, endpoint effects