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PCOS can be diagnosed if two of the three items are met, but other diseases causing hyperandrogenism, hyperprolactinemia, and abnormal thyroid function should be excluded

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The ability to track fibrotic processes through circulating collagen-based biomarkers offers a clinically relevant tool for patient management - enabling early identification of high-risk patients, personalized therapeutic strategies, and real-time monitoring of antifibrotic or stroma-targeting therapies 35,36,37