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The scientists commented that: “ regulation of the pro-inflammatory milieu of the ischemic retina can be enhanced by ARA290 and may be a useful [research agent] to ECFC-based cell [procedures] for ischemic retinopathies

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The clinical phenotype suggests an important role for collagen III in either the synthesis or deposition of heterotypic fibrils containing largely collagen I, but remarkably, the precise mechanism of disease is still unknown